According to settlement papers, McKesson "expressly denies" the government's charges, as well as those of a whistleblower, David Morgan, in a related civil lawsuit filed in New Jersey federal court.
In a prepared statement, the company said: "We continue to believe that the AWP (average wholesale price) claims against McKesson are without merit. McKesson adhered to all applicable laws and regulations, and we do not set AWPs. We did not manipulate drug prices, and did not violate any laws.
"However, when we weighed our conviction that we did not violate any laws against the inherent uncertainty of litigation, we determined that this settlement was in the best interest of our employees, customers, suppliers and shareholders."
Fishman said state governments may negotiate separately with McKesson to resolve claims based on their shares of the Medicaid overpayments.
He also said federal and state governments had recovered more than $2 billion from drug companies alleged to have reported inflated pricing information.
Whistleblowers can receive 25 percent of settlement amounts in False Claims Act cases, depending on how much work they contribute.
Neither Morgan nor his lawyer could be immediately located for comment. Morgan filed his lawsuit in 2005, and added McKesson as a defendant in 2006. The case remains under seal.
In morning trading, McKesson shares rose 0.5 percent to $91.83 on the New York Stock Exchange.
The case is U.S. ex rel. Morgan v. Express Scirpts Inc et al, U.S. District Court, District of New Jersey, No. 05-01714.
McKesson shares were up 0.4 percent to $91.72 in afternoon trading on the New York Stock Exchange.
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