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Tue Aug 13, 2013 9:29am EDT
Aug 13 (Reuters) - Eli Lilly and Co said its experimental lung cancer drug increased survival of patients in a late-stage trial, and the company plans to file for a U.S. marketing application before the end of 2014. Lilly shares were up 4 percent in premarket trading. The drug, necitumumab or IMC-11F8, was given to patients with advanced non-small cell lung cancer in combination with already-approved chemotherapy drug gemcitabine and cisplatin, and was compared with chemotherapy alone. "If approved, necitumumab could be the first biologic therapy indicated to treat patients with squamous lung cancer," Richard Gaynor, Lilly's vice president for product development and medical affairs, said in a statement. Earlier this year, Bristol-Myers Squibb Co. backed out of a collaboration to develop necitumumab and returned the full rights to Lilly. Necitumumab is a potential follow-up to the cancer drug Erbitux that came from Lilly's 2008 acquisition of ImClone. A separate late-stage trial of the drug was stopped in early 2011 after concerns that it was linked with blood clots. In that trial, called INSPIRE, the drug was being tested in combination with Lilly's Alimta cancer drug and the chemotherapy drug cisplatin. The company's stock closed at $54.05 on the New York Stock Exchange on Monday.
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