Tuesday, August 13, 2013

Reuters: Regulatory News: UPDATE 1-Lilly says lung cancer drug increased survival in late-stage trial

Reuters: Regulatory News
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UPDATE 1-Lilly says lung cancer drug increased survival in late-stage trial
Aug 13th 2013, 13:29

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Tue Aug 13, 2013 9:29am EDT

  Aug 13 (Reuters) - Eli Lilly and Co said its  experimental lung cancer drug increased survival of patients in  a late-stage trial, and the company plans to file for a U.S.  marketing application before the end of 2014.      Lilly shares were up 4 percent in premarket trading.      The drug, necitumumab or IMC-11F8, was given to patients  with advanced non-small cell lung cancer in combination with   already-approved chemotherapy drug gemcitabine and cisplatin,  and was compared with chemotherapy alone.       "If approved, necitumumab could be the first biologic  therapy indicated to treat patients with squamous lung cancer,"  Richard Gaynor, Lilly's vice president for product development  and medical affairs, said in a statement.      Earlier this year, Bristol-Myers Squibb Co. backed  out of a collaboration to develop necitumumab and returned the  full rights to Lilly. Necitumumab is a potential follow-up to  the cancer drug Erbitux that came from Lilly's 2008 acquisition  of ImClone.      A separate late-stage trial of the drug was stopped in early  2011 after concerns that it was linked with blood clots. In   that trial, called INSPIRE, the drug was being tested in  combination with Lilly's Alimta cancer drug and the chemotherapy  drug cisplatin.      The company's stock closed at $54.05 on the New York Stock  Exchange on Monday.  
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